Direct Absorption of Riboflavin Tetrabutyrate through Digestive Canal

Diseases of the Digestive Canal

Two-photon fluorescence microscopy of corneal riboflavin absorption through an intact epithelium.

Conditional (intestinal-specific) knockout of the riboflavin transporter-3 (RFVT-3) impairs riboflavin absorption.

Riboflavin (RF) is indispensable for normal cell metabolism, proliferation, and growth. The RFVT-3 protein (product of the Slc52a3 gene) is expressed in the gut with the expression being restricted to the apical membrane domain of the polarized intestinal epithelial cells. The relative contribution of RFVT-3 to total carrier-mediated RF uptake in the native intestine, however, is not clear. We ...

Investigating the Normal Digestive Canal Ultrasonography of Mature Persian Sturgeon for Providing Standard Approaches

Objective- This study was conducted to make a full understanding of the anatomic and ultrasonographic characteristics of digestive canal in Persian Sturgeon and provide standard approaches for performing digestive tract ultrasonography on this sturgeon species.Design - Experimental studyAnimals - 30 mature Persian sturgeons (Asipenc...

Functional involvement of RFVT3/SLC52A3 in intestinal riboflavin absorption.

Riboflavin, also known as vitamin B2, is transported across the biological membrane into various organs by transport systems. Riboflavin transporter RFVT3 is expressed in the small intestine and has been suggested to localize in the apical membranes of the intestinal epithelial cells. In this study, we investigated the functional involvement of RFVT3 in riboflavin absorption using intestinal ep...